Organoids - Mini Organs in a Dish
Organoids are three-dimensional (3D) cell culture systems that closely resemble the in vivo organ or tissue, which they are derived. These 3D Systems replicate the complex spatial morphology of a differentiated tissue, and allow biologically relevant cell-cell and cell-matrix interactions; ideally, sharing similar physiological response found within in vivo differentiated tissues. This is in contrast to traditional two-dimensional (2D) cell culture models that often bear little physical, molecular, or physiological similarity to their tissue of origin. Read more...
